Advanced Thyroid Cancer Cases: Surgical Perspectives and Updates on Adjuvant Therapies

Tuesday, October 20, 2026

11:15 AM - 12:15 PM PT

Location: 404B

Moderator(s)

Elizabeth E. Cottrill, MD, FACS,

Professor, Residency Program Director, Co-Director Thyroid & Parathyroid Center
Thomas Jefferson University Hospital
Philadelphia, PA, United States

Panelist(s)

Gregory W. Randolph, MD

Claire and John Bertucci Endowed Chair in Thyroid Surgical Oncology
Harvard Medical School
Westwood, Massachusetts, United States
David C. Shonka, Jr., MD

Professor
University of Virginia Medical Center
Charlottesville, Virginia, United States
Mark E. Zafereo, MD

Professor
MD Anderson Cancer Center
Houston, TX, United States

Disclosure(s):

Mark E. Zafereo, MD:

faculty for this accredited education activity has no relationship(s) with ineligible companies to disclose.

The session focuses on anaplastic thyroid cancer (identified gap analysis), poorly differentiated, medullary, and advanced well-differentiated thyroid cancers. The first goal of this session is to define advanced thyroid cancer and identify the diagnostic studies including imaging and molecular testing that are indicated to confirm advanced disease. The second goal is to discuss the specific molecular mutations and profiles in advanced thyroid cancers and the targeted and non-targeted treatment options available. Finally, the session will discuss and debate aspects of surgical decision making, appropriate surgical aggressiveness, and the role of adjuvant therapies and clinical trials. The session will use case presentations to illustrate state-of-the-art management of advanced thyroid cancer.

Learning Objectives:

define advanced thyroid cancer and recognize how it differs from the majority of thyroid malignancy.
Identify the specific mutations that drive advanced disease and corresponding targeted treatment options.
Debate the extent of surgical intervention and discuss the role of peri-operative adjuvant therapy in the management of advanced thyroid cancer.