(716) Oncologic and Functional Outcomes of Supracricoid Partial Laryngectomy in Management of Laryngeal Cancer

Introduction: Supracricoid partial laryngectomy (SCPL) is a reliable alternative in managing select laryngeal cancers. This study aims to characterize the oncologic and functional outcomes following SCPL.

Methods: A retrospective single-surgeon series of 56 consecutive patients, with primary or recurrent laryngeal squamous cell carcinoma (SCC), who underwent SCPL between 2006 and 2023 at a quaternary referral center. Demographic, intraoperative, and oncologic characteristics were collected through chart review. Kaplan-Meier estimates yielded 2- and 5-year oncologic outcomes, including local control, disease-specific survival, and overall survival, as well as times to decannulation and feeding tube removal.

Results: Patients with glottic (n=46) and supraglottic (n=10) SCC received SCPL with cricohyoidopexy (n=15) or cricohyoidoepiglottopexy (n=41). Notably, 46% of patients had persistent cancers following prior radiation/chemoradiotherapy (n=25) or surgical intervention (n=4), and 45% of tumors were locally advanced (T3 or T4). All patients were decannulated at a median of 29 days (range 13-90 days), and all but one achieved G-tube removal at a median of 89 days (range 27-468 days). At 2 and 5 years, local control rates were 80% and 80%; disease-specific survival rates were 92% and 88%; and overall survival rates were 84% and 81%. Laryngeal function was preserved in 84% of patients; 9 patients required subsequent total laryngectomy for oncologic salvage (n=6) and chronic aspiration (n=3).

Conclusions: Our findings indicate that SCPL achieves excellent oncologic and functional outcomes even in salvage settings. These outcomes align with established literature benchmarks and reinforce SCPL as a viable alternative to nonsurgical strategies and total laryngectomy for carefully selected patients.