(233) Resolution of Guttate Psoriasis Following Tonsillectomy in a Patient With Chronic Tonsillitis

Introduction: Guttate psoriasis has been associated with streptococcal infections, suggesting that chronic tonsillitis may serve as a persistent immunologic trigger. This study explores whether tonsillectomy can lead to clinical resolution of guttate psoriasis in a patient with chronic tonsillitis.

Methods: This study was designed as a single-patient case report conducted in 2025, involving a 28-year-old male with guttate psoriasis and chronic tonsillitis evaluated in a tertiary otolaryngology setting. The patient had a history of recurrent tonsillitis and persistent cutaneous lesions despite prior medical management. Bilateral extracapsular tonsillectomy was performed as the primary intervention. Clinical outcome was assessed through dermatologic examination, focusing on the presence and resolution of psoriatic lesions during postoperative follow-up. The primary independent variable was surgical removal of chronically inflamed tonsillar tissue, and the primary outcome measure was clinical resolution of guttate psoriasis. No formal statistical analyses were performed, given the descriptive nature of this case report.

Results: Following bilateral extracapsular tonsillectomy, the patient demonstrated complete clinical resolution of guttate psoriatic lesions within two weeks of surgery. No additional dermatologic treatments or systemic immunomodulatory therapies were required during the postoperative period. The postoperative course was uncomplicated, and no recurrence of cutaneous lesions was observed during early follow-up. Given the descriptive nature of this single-patient case report, no statistical analyses, confidence intervals, or p values were applicable.

Conclusions: In this case, tonsillectomy was followed by rapid and complete resolution of guttate psoriasis, supporting a potential role of chronic tonsillitis as an immunologic trigger. While this finding suggests that tonsillectomy may be beneficial in selected patients, the absence of comparative data limits generalizability and warrants further investigation in larger studies.